Sweet tooth: how blood sugar migration in diabetes affects cavity development

Masae KUBONIWA, Akito SAKANAKA
Department of Preventive Dentistry

Researchers from The University of Osaka found migration of glucose and fructose from the blood to saliva drives oral microbiome dysbiosis in patients with type 2 diabetes, increasing the development of dental caries. This suggests that glycemic control could be an effective strategy for controlling dental caries in this population.

The article, “Diabetes alters the supragingival microbiome through plasma‑to‑saliva migration of glucose and fructose,” was published in Microbiome at DOI:https://doi.org/10.1186/S40168-025-02256-X